The Stratasys J750 3D printer delivers unavailed aesthetic performance including true, full-color capability with the texture mapping and color gradients. Create prototypes that look, feel and operate like finished products, without the need for painting or assembly, thanks to the Stratasys J750’s wide range of material properties.
With this, students can easily experience both the prototyping and testing stages of the manufacturing process, helping to prepare them for what they will experience once they enter the workforce. The high quality materials available with the J750 also allow for the creation of highly intricate and realistic models, perfect for helping medical students with research.
The wide color spectrum, combined with the fine-finish, multi-material capability, let’s the Stratasys J750 produce parts with an incredible array of characteristics. Prototypes that need to look, feel and function like future products are possible in a single print operation, with minimal to no finishing steps, like painting, sanding or assembly.
With such an innovative machine comes a variety of user applications, such as:
Jigs & Fixtures
Join PADT’s Sales executive Jeff Nichols and 3D Printing Application Engineer James Barker from 11:00 AM – 12:00 PMMST AZ for an in depth look at how the Stratasys J750 stacks up against it’s competition, and how it’s various attributes help to make it the perfect fit for institutions such as yours!
Don’t miss this unique opportunity to bring the future of manufacturing into your classroom or workplace, secure your spot today!
This is the third installment in our review of all the different products and services PADT offers our customers. As we add more, they will be available here. As always, if you have any questions don’t hesitate to reach out to firstname.lastname@example.org or give us a call at 1-800-293-PADT.
PADT is in the business of helping people who make products. So most people think of us as a provider of tools and services. What they do not know is that PADT actually has a few of its own products. The most successful of these is our line of Support Cleaning Apparatus systems, abbreviated as SCA. These devices are used to remove soluble support material from parts 3D printed in Stratasys Fused Deposition Modeling Systems. They are robust machines manufactured and serviced by PADT, but sold through the Stratasys worldwide sales channel. As of July of 2017, over 10,800 units have been delivered to Stratasys.
Optimized Performance for Hands-Off Part Cleaning
The Stratasys 3D Printing systems that use Fused Deposition Modeling extrude plastic through a heated nozzle to build parts one layer at a time. There are actually two nozzles. One puts down the building material and the other a support material that is dissolved in warm water that is slightly base. The best way to remove that support material is to put it into a warm bath where the part is gently tumbled so that the water can works its way evenly into the part. Stratasys tried several solutions for a companion washing system and eventually came to PADT and asked if we would try our hand at building a robust and efficient system.
The result was the SCA-1200. Launched at the end of 2008 it met the design requirements for reliability, part cleaning time, and noise. Over 7,000 of these systems were shipped and saw heavy usage. In fact, if you have a Stratasys FDM system there is a good chance you have an SCA-1200. It contained a unique shower head design that was optimized with simulation, and a modular assembly that could be repaired easily in the field.
Based upon the success and lessons learned from the SCA-1200, we released the SCA-1200HT in 2014. With the same basic form factor, this design replaced the off-the-shelf magnetically coupled pump with a simpler and more reliable custom design from PADT. The new unit also had a more pleasing visual design, several usability enhancements, and a greater temperature range. It has sold over 3,000 units and continues to be a popular system. The latest release includes a no-temperature setting that allows it to be used to clean Stratasys Polyjet parts.
The success of both system lead to a request to look at building a larger machine that could clean more parts at one time as well as larger parts. The SCA 3600 has three times the volume but shares many internal parts with the SCA-1200HT. Both of the new systems are doing well in the field with even better reliability and faster part cleaning times. They are also simpler to debug and repair.
The SCA systems are sold as stand alone devices or are bundled with key Stratasys FDM machines. You can learn more about them on our SCA page: www.padtinc.com/sca or you can contact whoever you buy your Stratasys equipment from.
Here is a video for the SCA-1200HT that talks all about what it does:
Practicing what We Preach
One of the most rewarding aspects of designing and manufacturing the SCA family of products was that it forced us to practice what we preach. We talk to companies every day about using simulation, 3D Printing, design for manufacturing, proper product development processes, and many more things needed to get a product right. With the SCA we were the customer. We had to Walk the Walk or stop talking the talk.
It has been a phenomenal experience that has made us even better at helping our customers produce their new products. We used CFD to optimize the gentle agitation design and shower head and worked closely with our vendors to minimize the cost of manufacturing. The worst part was that when the schedule slipped, we couldn’t blame the customer (only slightly joking). One of the best set of lessons came from doing the repair and refurbishment of systems that failed. Even though the failure rate was low, we learned a lot and were able to make improvements to future designs. Now when we sit across from a customer and talk about the design, test, and manufacture of their product, we can really say that we understand where they are coming from.
Performance so good, you won’t believe it’s so easy to use!
The Stratasys F123 3D Printer Series demands less knowledge and experience, while meeting even the most advanced rapid prototyping expectations and needs, helping to make it the perfect machine for the classroom. This Series excels at all stages of the design prototyping process, from draft-concept iterations – to complex design verification – to high-quality functional prototypes.
Enhanced 3D printing capabilities of the F123 series include:
New user interface
Remote print monitoring
Improved software experience with GrabCAD Print
Easy material change out
Auto material changeover
Join PADT’s Application Engineer James Barker and Sales Executive Jeff Nichols for a webinar that will provide an in depth look at all three machines that make up the all new F123 3D Printer Series (F170, F270, & F370).
PADT is excited to introduce the newest polyjet material available from Stratasys, Agilus30! Agilus30 is a superior Rubber-like PolyJet photopolymer family ideal for advanced design verification and rapid prototyping.
Get more durable, tear-resistant prototypes that can stand up to repeated flexing and bending. With a Shore A value of 30 in clear or black, Agilus30 accurately simulates the look, feel and function of Rubber-like products. 3D print rubber surrounds, overmolds, soft-touch coatings, living hinges, jigs and fixtures, wearables, grips and seals with improved surface texture.
Agilus30 has applications in a number of areas, including:
Tooling needing rubber-like characteristics
Overmolding & many more!
Want to know more about PolyJet’s toughest flexible material to date?
Join PADT’s 3D Printing Application Engineer James Barker along with Stratasys Materials Business Manager Ken Burns for a presentation on the various benefits and attributes that Agilus30 has to offer, which machines are compatible with it, and how companies are making use of it’s unique capabilities.
It was my first time visiting New Orleans. I have heard many stories of how good the food is and how everyone is really nice there so I was excited to visit this city for a business trip. Stratasys Launch 2017! There was some buzz going on about some new FDM printers that Stratasys has been working on and I was really excited to see them and hear what sets them apart from the competition. Rey Chu (Co-Owner of PADT), Mario Vargas (Manager of 3D Printer Sales), Norman Stucker (Account Executive in Colorado), and I (James Barker, Application Engineer) represented PADT at this year’s Launch.
The city did not disappoint! I ate the best gumbo I’ve ever tried. Below is a picture of it with some Alligator Bourbon Balls. The gumbo is Alligator Sausage and Seafood. Sooooo Good!!
My last night in New Orleans, Stratasys rented out Mardi Gras World. That is where they build all the floats for Mardi Gras. They had a few dancers and people dressed up festive. I was able to get a picture of Rey in a Mardi Gras costume.
After dinner at Mardi Gras World, I took Rey and Mario down Bourbon Street one last time and then we went to Café Du Monde for their world famous Beignets. Everyone told me that if I come home without trying the Beignets, then the trip was a waste. They were great! I recommend them as well. Below is picture of Mario and me at the restaurant.
As you can see we had a fun business trip. The best part of it was the unveiling of the new FDM printers! Mario and I sat on the closest table to the stage and shared the table with Scott Crump (President of Stratasys and inventor of FDM technology back in 1988). These new printers are replacing some of Stratasys entry level and mid-level printers. What impressed me most is that they all can print PLA, ABS, and ASA materials with the F370 being able to print PC-ABS. You also can build parts in four different layer heights (.005, .007, .010, and .013”), all while utilizing new software called GrabCad Print.
GrabCad Print is exciting because you can now monitor all of you Stratasys FDM printers from this software and setup queues. What made me and many others clap during the unveiling is that with GrabCad Print you no longer have to export STL files! You can import your native CAD assemblies and either print them as an assembly or explode the assembly and print the parts separately.
Everyone wants a 3D Printer that can print parts faster, more accurately and is dependable. You get that with the family of systems! Speed has increased big time, they are twice as fast as the Dimension line of FDM printers. Stratasys has published the accuracy of these new printers to be ±.008” up to a 4 inch tall part and then every inch past 4 inches, you add another .002”. These machines are very dependable. They are replacing the Uprint (Uprint SE Plus is still current), Dimension, and Fortus 250 machines that have been workhorses. Many of our customers still have a Dimension from 2002 when they were first launched. In addition to the 43 existing patents that Stratasys has rolled into this phenomenal product, they have an additional 15 new patents that speaks volumes as to the innovation in these 3D printers.
Stratasys Launch was a blast for me. Seeing these new printers, parts that were printed from them, and understanding why these are the best FDM printers on the market was well worth my time! I look forward to helping you with learning more about them. Please contact me at email@example.com for more information. If you would like to hear my recorded webinar that has even more information about the new F170, F270, and F370, here is the link. Or you can download the brochure here.
We have great customers. The kind of cusomers that call up and ask “Hey, what do you think about having a Tesla test drive event for PADt employees” Duh. Yes. Please provide contact information.
Then we thought this was an event better shared with other techno-speed-nerds. The Tempe Tesla show room people liked the idea so we put together an event for our ANSYS and Stratasys customers. (Just another reason to buy from us)
The basic idea was simple, stop on by the PADT parking lot in Tempe and drive a Tesla Model S or Model X, or both. The Tesla people brought along their technical person and the test drive people were also very knowledgable about all the features in the three vehicles they let us drive. The course left the PADT parking lot, drove up to Elliot, then entred to 101, and then get off at Warner or Rey and head back, while the brave Tesla employee tried to keep cool. Especially when Oren was driving.
For many of us, this was the first time we had driven one. Let me just say that the common factor across employees and cusotmers is that everyone had an ear-to-ear grin on their face when they got back from their test drive. These cars are not just fast (large numbers of electrons pushed through big motors equals lots of torque right away) but they are brilliantly engineered. From the user interface, to the seats to, to the suspension. Everything is done right. As a group of engineers that was almost as exciting as the raw power and impecable styling of the cars.
It was a true nerdfest. We spent 10 minutes discussing regenerative breaking schemes and the idea of using regeneration all the time when you lift off the accerator instead of putting your foot on the break to slow down slightly. This is the type of paradigm shift that disrupts around one hundred years of automotive legacy. Why does the accelrator pedal have to be an accelerator pedal. Why can’t it be an input for acceleration and deceleration based on position? We also spent even more time (I’m embarassed to say how long) talking about charging. And then the topic turned to autonomous driving and the sensors used. Good times. Good times.
PADT’s relationships with Tesla actually goes way back. When they were first starting out and were just a handfull of engineers, we provided some ANSYS training and did a consulting job for them on thermal management for an early battery system. So we proudly count them as a happy PADT customer. And of course PADT worked on the large Blink chargers and has supported many companies that are suppliers to tesla.
Look for similar events in the future. No sales or seminars, just smart-people-fun type of events.
Although February is a short month, we have lots of activities scheduled to talk about new releases from both ANSYS and Stratasys as well as a STEM and Medtech event. Take a look for details below or visit the bottom of our home page to see the latest.
Arizona Science Bowl
ASU West Campus
PADT will be attending this great event for middle and high schools. Dr. Bhate will be speaking to the middle school students
Stratasys is introduce some new products and you are invited to attend online to learn how once again they will advance 3D Printing to the next level. PADT’s engineers will not just share information about these new systems, they will also explain what we thing is important about each machine and what its new advantages are.
ANSYS is rolling out a new version of their entire software platform, and we are offering seminars to help users understand what is new and cool. This first webinar will be focused on ANSYS Mechanical APDL and what is going on way deep under the hood.
Medtech has grown a lot in Arizona over the past couple of years, so the Tech Council is putting on an event for everyone involved to get together to network and learn. PADT will have a booth and will be talking about 3D Printing in medical devices. If you are at all involved in medical technology, you should attend.
ANSYS is rolling out a new version of their entire software platform, and we are offering seminars to help users understand what is new and cool. This second webinar will be focused on ANSYS HPC licensing and how that has changed.
Our work on 3D printed honeycomb modeling that started as a Capstone project with students from ASU in September 2015 (described in a previous blog post), was published in a peer-reviewed paper released last week in the proceedings of the SFF Symposium 2016. The full title of the paper is “A Validated Methodology for Predicting the Mechanical Behavior of ULTEM-9085 Honeycomb Structures Manufactured by Fused Deposition Modeling“. This was the precursor work that led to a us winning an 18-month award to pursue this work further with America Makes.
Download the whole paper at the link below:
Abstract ULTEM-9085 has established itself as the Additive Manufacturing (AM) polymer of choice for end-use applications such as ducts, housings, brackets and shrouds. The design freedom enabled by AM processes has allowed us to build structures with complex internal lattice structures to enhance part performance. While solutions exist for designing and manufacturing cellular structures, there are no reliable ways to predict their behavior that account for both the geometric and process complexity of these structures. In this work, we first show how the use of published values of elastic modulus for ULTEM-9085 honeycomb structures in FE simulation results in 40- 60% error in the predicted elastic response. We then develop a methodology that combines experimental, analytical and numerical techniques to predict elastic response within a 5% error. We believe our methodology is extendable to other processes, materials and geometries and discuss future work in this regard.
Building on the worldwide success of previous products in the family, PADT has just released the new SCA 3600, a large capacity cleaning system for removing the support material from Stratasys FDM parts. This new system adds capacity and capability over the existing benchtop SCA-1200HT System.
The SCA 3600 can dissolve support from all the SST-compatible materials you use – ABS, PC, and nylon. A “no heat” option provides agitation at room temperature for the removal of Polyjet SUP706 material as well. The SCA 3600’s versatility and efficient cleaning performance are built on the success of earlier models with all the features you have come to expect, in a larger and more capable model.
Since the launch of the original SCA-1200 in 2008, PADT has successfully manufactured and supported the SCA family of products for users worldwide. Common requests from desktop SCA users were for a larger system for bigger parts, the ability to clean many parts at the same time, and the option to remove supports from PolyJet parts. The SCA 3600 is the answer: Faster, larger, and more capable.
SCA 3600 Key Features are:
Removes soluble support from ABS, PC, and nylon 3D printed FDM parts
Removes soluble support from PolyJet 3D Printed parts
User-selectable temperature presets at 50, 60, 70, and 85°C and “No Heat” for PolyJet
Uses cleaning solutions from Stratasys
Unique spray nozzle optimizes flow coverage
230 VAC +/- 10%, 15A
Includes rolling cart for easy movement, filling, and draining.
Capacity: 27 gal / 102 L
Size: 42.8″ x 22.8″ x 36.5″/ 1,086 x 578 x 927 mm
16” x 16” x 14” / 406 x 406 x 356 mm removable large parts basket
Integral hinged lid and small part basket
Stainless steel tub and basket
Over temperature and water level alarms
Automatic halt of operation with alarms
Field replaceable sub-assemblies
Regulatory Compliance: CE/cTUVus/RoHS/WEEE
You can download our new brochure for both systems:
If you are interested in learning more or adding an SCA 3600 to your additive manufacturing lab, contact your Stratasys reseller.
Official copies of the press release can be found in HTML and PDF.
New 3D Printing Support Cleaning Apparatus Features Large Capacity for Stratasys FDM Systems
Offered Worldwide, the SCA 3600 is Big Enough to Handle Large 3D Printed Parts, Effortlessly Dissolving Support Material
TEMPE, Ariz., November 17, 2016 – Phoenix Analysis & Design Technologies, Inc. (PADT), the Southwest’s largest provider of simulation, product development, and rapid prototyping services and products, today introduced its new SCA3600 3D Printing Support Cleaning Apparatus (SCA). The systems are sold exclusively by Stratasys, Ltd. (SSYS) for use with its FORTUS line of 3D Printers. The hands-free support removal technology is a huge advantage to people who use Fused Deposition Modeling (FDM) systems for their 3D Printing.
“With more than 10,000 of our benchtop SCA units in the field, we gathered a wealth of knowledge on performance and reliability,” said Rey Chu, Co-owner and Principal of PADT. “We used that information to design and manufacture a system that cleans larger parts, or multiple small parts, while keeping the speed, easy maintenance and great user experience of the benchtop system.”
A powerful upgrade over PADT’s successful SCA-1200HT and SCA-1200 support removal products that have been in use around the world since 2008, the SCA 3600 features a simpler, more user-friendly design. The new versatile SCA offers temperature choices of 50, 60, 70 and 80 degrees Celsius, as well as no-heat, that readily cleans supports from all SST compatible materials – ABS, PC and Nylon. The SCA 3600 also features a large 16” x 16” x 14” parts basket, 3400 watts of heating for faster warm-up and a wheeled cart design for mobility.
The advantages of the system were highlighted by Sanja Wallace, Sr. Director of Product Marketing and Management at Stratasys, Ltd. when she commented, “the addition of the SCA 3600 as an accessory to our very successful FORTUS systems simplifies the support removal process with increased speed and capacity for multiple large parts.”
Once parts are printed, users simply remove them from their Stratasys FDM system, place them in the SCA 3600, set a cleaning cycle time and temperature, and then walk away. The device gently agitates the 3D printed parts in the heated cleaning solution, effortlessly dissolving away all of the support material. This process is more efficient and user friendly than those of other additive manufacturing systems using messy powders or support material that must be manually removed.
Phoenix Analysis and Design Technologies, Inc. (PADT) is an engineering product and services company that focuses on helping customers who develop physical products by providing Numerical Simulation, Product Development, and Rapid Prototyping solutions. PADT’s worldwide reputation for technical excellence and experienced staff is based on its proven record of building long term win-win partnerships with vendors and customers. Since its establishment in 1994, companies have relied on PADT because “We Make Innovation Work.” With over 80 employees, PADT services customers from its headquarters at the Arizona State University Research Park in Tempe, Arizona, and from offices in Torrance, California, Littleton, Colorado, Albuquerque, New Mexico, and Murray, Utah, as well as through staff members located around the country. More information on PADT can be found at http://www.PADTINC.com.
What do you get when you combine a motivated student leader, enthusiastic classmates, a worldwide online community, and the latest 3D Printing technology from Stratasys? You give children around the world a cool way to hold things again. That is what happened when high school student Rahul Jayaraman of Basis Chandler decided to take part in a project called Enabling The Future. They describe themselves as “A global network of passionate volunteers using 3D Printing to give the world a ‘helping hand'” by designing a wide variety of prosthetic hands for kids that can be printed and assembled by volunteers.
Local news station, KSAZ FOX 10 Phoenix stopped by PADT while we were printing three hands in our Stratasys FORTUS 450 to interview Rahul and talk to us about the project. It gives a great summary:
And Channel 3, KTVK, came to the assembly event at Basis Chandler:>
3D Printing is a fantastic technology for one simple reason, it enables almost anyone to manufacture parts. All you need is a good design. And that is where the people at Enabling the Future come in. Check out their website to see some great examples of how their volunteer work changes so many lives. Have a box of tissue handy if you watch the videos…
This is how the project works. A leader like Rahul takes the initiative to sign up for the project. He then chooses which of the many designs he wants to make. For this first go around, he picked a general design from Thingiverse called the Raptor Reloaded. Next they needed the hardware you could not 3D Print – screws springs, velcro, and bits and pieces that hold the design together. For this they needed to raise $25 per hand so Rahul was given the opportunity to learn how to raise money, a very useful skill.
PADT’s Dhruv Bhate and the rest of our 3D Printing team worked with Rahul to get the design just right and then 3D Print the hands. That will be done this week and this weekend the next phase will take place. Rahul and a large number of his classmates from Basis Chandler will get together at the school this weekend to put thirty or so hands together. They will then box them up and another volunteer group, www.HandChallenge.com, will ship them to kids in the developing world that need them.
Here is a video from Tom Fergus from Fox10 showing a closeup of the hand in action:
We at PADT love projects like this because it is win-win-win. The students get a chance to run a complicated project by themselves, learning the skills they will need later in life to organize, manage, and finish a project. PADT wins because we can contribute to our chosen area of charity, STEM education, in a way that benefits others beyond a given school. And the big winners are the kids around the world that receive a new and cool way to grab hold of life.
We will have sample hands at our open house next Thursday: Nerdtoberfest as well as an update when we get feedback from the distribution of the hands.
Is PolyJet MED610 truly biocompatible? And what does that mean anyway?
A couple of months ago, our product development team contacted me to see if I could 3D print them a small bio-compatible masking device that was needed for temporary attachment to an invasive device prior to insertion for surgery. That led me to investigate all the different bio-compatible materials we did have access to at PADT on our FDM (Fused Deposition Modeling) and PolyJet machines. Given the tiny size and high detail required in the part, I decided to opt for PolyJet, which does offer the MED610 material that is claimed to be biocompatible. As it so happens, we have an Objet Eden 260V PolyJet machine that has been dedicated to running MED610 exclusively since it’s installation a year ago.
We printed the mask, followed all the post-processing instructions per supplier recommendations (more on that later) and delivered the parts for further testing. And that is when I asked myself the questions at the top of this post.
I set off on a quest to see what I could find. My first stop was the RAPID conference in (May 2016), where the supplier (Stratasys Inc.) had a well-staffed booth – but no one there knew much about MED610 apart from the fact that some orthodontists were using it. I did pick up one interesting insight: one of the engineers there hypothesized that MED610 was not very popular because it was cost-prohibitive since its proper use required machine dedication. I then went to the Stratasys Direct Manufacturing (a service bureau owned by Stratasys) booth, but it turned out they don’t even offer MED610 as a material option for service jobs – presumably because of the low demand for this material, consistent with our own observations.
So I took a step back and began searching for all I could find in the public domain on MED610 – and while it wasn’t much, here is the summary of my findings that I hope help anyone interested in this. I categorize it in three sources of information: claims made by the supplier, published work on in vitro studies and finally, some in vivo animal trials. But first, we must ask…
What does it mean for a Material to be Biocompatible?
A definition by Williams (The Williams Dictionary of Biomaterials, 1999) is in order: “Biocompatibility is the ability of a material to perform with an appropriate host response in a specific application.” So if PolyJet MED610 is to be called biocompatible, we must ask – what application do we have in mind? Fortunately, the supplier has a recommendation.
MED610 was launched by Objet in 2011 (Objet was acquired by Stratasys in 2012) as a biocompatible material, ideal for “applications requiring prolonged skin contact of more than 30 days and short-term mucosal-membrane contact of up to 24 hours“. Stratasys claims that parts printed according to Objet MED610 Use and Maintenance Terms were evaluated for biocompatibility in accordance with standard “DIN EN ISO 10993-1: 2009, Biological Evaluation of Medical Devices-Part 1: Evaluation and testing within a risk management process. This addresses cytotoxicity, genotoxicity, delayed hypersensitivity, and USP plastic Class VI, which includes the test for irritation, acute systemic toxicity and implantation”. Unfortunately, the actual data from the biocompatibility study conducted by Objet have not been made publicly available.
It is important to remember that Stratasys publishes a “Use and Maintenance Terms” document that details the steps needed not just to clean the part after printing, but also on the proper setup of the machine for ensuring best chances of meeting biocompatibility requirements. These are published online at this link and include a 3 hour soak in a 1-percent NaOH solution, a 30 min soak in IPA and multiple water jet rinses, among other steps. In other words, the claimed biocompatibility of MED610 is only valid if these instructions are followed. These steps are primarily driven by the need to completely remove supports and any support-residue, but it is not clear if this is needed if a part can be printed without supports. Given such strong process dependencies, it is only to be expected that Stratasys provide a disclaimer at the end of the document clarifying that the users of their machines are responsible for independently validating biocompatibility of any device they make with MED610.
The next question is: have there been any relevant published, independent studies that have used MED610? In my search, I could only find two instances, which I discuss below.
Primary Human Cells Response (In Vitro)
In a recent (January 2016) study published in the Journal of Medical and Biological Engineering, Schmelzer et al. studied the response of primary human cells to four 3D printed materials in vitro: ABS, PC, PLA and MED610 – the only such study I could find. All samples instead went through a 100% ethanol brief rinse and were washed 5 times with de-mineralized water – this seems like a less stringent process than what the supplier recommends (3 hour 1-percent NaOH solution soak, 30 minutes IPA soak and 10 times waterjet blasting) but was designed to be identical across all the materials tested.
There were some very interesting findings:
Different cells had different responses:
MED610 had the most negative impact on cell viability for keratinocytes (epidermal cells that produce keratin) – and the only material that showed statistically significant difference from the control.
For bone marrow mesenchymal (stem) cells, a different effect was observed: direct culture on ABS and PC showed significant growth (7X compared to control) but MED610 and PLA showed no significant effect
Surface Roughness influences cell attachment and proliferation:
In agreement with other work, the authors showed that while rougher surfaces promote initial cell attachment, subsequent cell proliferation and overall cell numbers are higher on smoother surfaces. The MED610 samples had rougher surfaces than the FDM samples (possibly due to the use of the “matte” finish option) and could be one of the contributors to the observed negative effects on cell viability, along with the leached contents from the specimen.
Glaucoma Drainage Device (In Vivo, Rabbit studies)
The devices were printed on a Connex 350 PolyJet machine, after which the supports were removed from the devices with a water jet and “were repeatedly washed and inspected for consistency and integrity.” Tubes were attached with Silicone adhesive and the entire assembly was then “washed and sterilized with a hospital-grade hydrogen peroxide system before use”. The researchers did not examine the cellular and extracellular reactions in great detail, but did conclude that the reactions were similar between the MED610 device and the more standard polypropylene injection-molded device.
A short video recorded by some of the researchers as part of a Bioprinting course also provides some details into the 3D printing aspects of the work done.
In conclusion, the question I posed at the start of this post (Is PolyJet MED610 truly biocompatible?) is too simplistic. A process and a material together are not sufficient – there are procedures that need to be defined and controlled and further and more importantly, biocompatibility itself has to be viewed in the context of the application and the specific toxicity and interaction demands of that application. And that brings us to our key takeaways:
MED610 is only recommended at best for applications requiring prolonged skin contactof more than 30 days and short-term mucosal-membrane contact of up to 24 hours and there is no data to dispute the suppliers claim that it is biocompatible in this context once all recommended procedures are implemented
The work done by Australian researchers in using PolyJet MED610 for devoloping their Glaucoma Drainage Device in animal trials is perhaps the best example of how this material and the technology can be pushed further for evaluating designs and hypothesis in vivo when really fine features are needed. Stratasys’s FDM PC-ISO or ABS M30i materials, or other FDM extrusion capable materials like PLA, PCL and PLGA may be better options when the resolution allows – but this is a topic for a follow-on blog post.
More in vitro work needs to be done to extend the work done by Schmelzer et al., which suggests that MED610 potentially has leachables that do impact cell viability negatively. Specifically, effects of surface finish (“matte” vs “gloss”) and sterilization on cell viability is a worthwhile follow-on step. In the interim, MED610 is expected to perform well for mucosal membrane contact under 24 hours (and why this is a great technology for dental guides and other temporary in-mouth placement).
If you have any thoughts on this matter or would like to collaborate with us and take advantage of our access to a PolyJet printer that is dedicated to MED610 or other bio-compatible FDM materials, as well as our extensive post-processing and design & analysis facilities, please connect with me on LinkedIn or send us a note at firstname.lastname@example.org and cite this blog post.
Schmelzer, E., Over, P., Gridelli, B., & Gerlach, J. (2016). Response of Primary Human Bone Marrow Mesenchymal Stromal Cells and Dermal Keratinocytes to Thermal Printer Materials In Vitro. Journal of Medical and Biological Engineering, 36, 153-167.
Ross C, Pandav S, Li Y, et al. Determination of Bleb Capsule Porosity With an Experimental Glaucoma Drainage Device and Measurement System. JAMA Ophthalmol.2015;133(5):549-554. doi:10.1001/jamaophthalmol.2015.30.
Our loop around the Southwest with the new Stratasys J750 Full Color 3D Printer finished strong with a well attended gathering at ASU’s Skysong in Scottsdale. The event was so popular, Channel 10 did a story on it. Over 130 people signed up to learn more about this fantastic device, get caught up on latest industry trends, and talk with other users of Additive Manufacturing.
This event had a great mix of users from multiple industries as well as students and people wanting to just learn more about the technology.
The presentations were a big hit from every seminar, and Dhruv’s was especially popular in Arizona. You can download the presentations here:
During the breaks and after the presentations, we had a chance to interact one-on-one with customers, show off parts, and answer questions. If you have any questions, please feel free to contact us at 480.813.4884 or email@example.com.
Lastly, we were visited by local TV channel 10, KSAZ who did a short but really informative segment on the show and the Stratasys J750:
The second stop on our trip around the Southwest for Stratasys’ new J750 Full Color 3D Printer was in fantastic downtown Salt Lake City. This device is reinventing 3D printing, and we are showing it off in person so people can see it up close along with holding incredible parts it makes in their hands.
The 3D Printing community in Utah is very mature and the attendees were mostly very experienced users of many different additive manufacturing technologies. So we focused on real world applications for the J750 as well as other Stratasys systems.
We were fortunate enought to have a customer, Ultradent, present the fantastic ways that they use their FDM and Polyjet printers to make prototypes, tooling, and production parts.
As is usual in this type of an event, the discussion between and after presentations are the best part. People from Aerospace, sporting goods, medical devices, and consumer products swapped stories, suggestions, and tips.
It was also a family affair. with Jame Barker’s latest family addition was in attendence to help spread the word on the value of 3D Printing with Stratasys solutions:Beyond the little guy, the other hit of the afternoon was the J750. As seasoned additive manufacturing profesionals they see the incredible leap forward this machine represents – truly reinventing 3D Printing and opening up a huge range of oportunities.
Denver was the first stop on a trip around the Southwest for Stratasys’ new J750 Full Color 3D Printer. We are showing this machine that is reinventing 3D printing off in person so people can see the device up close and hold the incredible parts it makes in their hands.
The Denver event was hosted by St. Patrick’s Brewery in Littleton, right down the street from PADT’s Colorado Office. Several customers and PADT employees gave talks on how to better use 3D Printing, including a presentation from Mario Vargas on the new Stratasys J750.
On top of all of that, local radio station KDMT, Denver’s Money Talk 1690, did a live broadcast from the event. You can listen in here. Again, PADT employees and customers talked about 3D Printing as well as the new Stratasys J750.
We also made the local paper, check that out here.